Nexium capsules should be taken by mouth at least one hour before food and at the same time every day, unless otherwise directed by your doctor. Do not crush or chew the Nexium capsule. Read on the dosage and administration of NEXIUM® (esomeprazole magnesium) totreatthe symptoms of acid reflux disease. Your doctor may adjust your dose as needed. To prevent erosive esophagitis from coming back, your doctor may want you to take 20 mg once a day for up to 6 months. NEXIUM prescription and dosage information for physicians and health care professionals. Pharmacology, adverse reactions, warnings, and NEXIUMside effects. Esomeprazole, sold as Nexium, treats acid reflux. Here’s our guide to dosing Nexium for adults and children, and for times when dosage changes may be needed. Adults Starting dosage is 40 mg twice daily4 (varies with the individual patient) as long as clinically indicated. A maximum dosage of 20 mg once daily is recommended for patients with severe. Find patient medical information for Esomeprazole (Nexium) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Detailed dosage guidelines and administration information for Nexium Capsules (esomeprazole magnesium). Includes dose adjustments, warnings and precautions. Adjust dose according to prescribing information if needed. The standard Nexium dosage for heartburn is 1, 20 mg capsule for up to 14 days. Use our Nexium dosage chart to find the recommended and maximum dosage of Nexium.